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JCI Insight - Hepatocyte-derived DPP4 regulates portal GLP-1 bioactivity, modulates glucose production, and when absent influences NAFLD progression
The medication continues working to maintain that new set point, which is why discontinuation often leads to weight regain
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If a prescriber writes for "semaglutide 2 mg weekly for weight loss," Anthem denies it as off-label use of a diabetes drug, even though 2 mg is within the Wegovy dose range
