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Retatrutide appeared to induce lean mass loss in similar proportions to GLP-1RAs alone, whereas PTT-A has shown robust fat reduction without significant decrease in muscle mass, highlighting the potential of selective multi-agonists to preserve skeletal muscle during weight loss [66, 67]
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[DOI] [PMC free article] [PubMed] [Google Scholar] 140.Pocai A., Carrington P.E., Adams J.R., Wright M., Eiermann G., Zhu L., Du X., Petrov A., Lassman M.E., Jiang G., et al
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