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Sex Hormones and Type 2 Diabetes Treatment: How metformin and GLP-1 agonists may work differently in women - American Medical Women's Association
One the other hand, SGLT2 inhibitors specifically alter renal hemodynamics and then reduce intraglomerular pressure [21, 24–26], and attenuate diabetes-associated hyperfiltration and tubular hypertrophy, as well as reduce the tubular toxicity of glucose to directly protect kidney [27]
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Combined with limited insurance coverage and high out-of-pocket costs, these shortages have prompted some patients to turn to compounded versions as alternatives
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