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semaglutide for pcos vs metformin Therapeutic Potential of Glucagon-like Peptide-1 Agonists in Polycystic Ovary
Indeed, in obese mice it was seen that antibiotic-induced depletion of Bacillota and Bacteroidota alters the pool of intestinal metabolites, in particular by increasing taurocholic acid, which in turn stimulates the release of GLP-1 from L cells, improving glucose tolerance ( Bacteroides , members of the family Lachnospiraceae , and the beneficial genus Bifidobacterium , which was linked to lowered intestinal inflammation and improved glycemic control (27)
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