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If not, continue for 2-3 cycles and if you don’t notice improvement, try steps 1 or 2 above
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Immunohistochemical staining and western blot analysis revealed that SNL increased the activation of microglia and astrocytes in the dentate gyrus of the hippocampus, along with elevated expression of pro-inflammatory cytokines such as TNF-α, IL-1β and IL-6, which were significantly reversed by exendin-4 treatment [68]