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In addition to the GLP‐1 produced in the small intestines after food intake, GLP‐1 is also produced in the NTS of the brain and is released as a neurotransmitter in several brain regions
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The review revisited SUSTAIN-6, where semaglutide-treated patients showed a hazard ratio of 1.76 for retinopathy complications compared with placebo.² The discussion has since shifted toward whether rapid metabolic change—rather than direct retinal toxicity—may explain the signal
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