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Cardiorenal Protection: Potential of SGLT2 Inhibitors and GLP-1 Receptor Agonists in the Treatment of Type 2 Diabetes | Diabetes Therapy | Springer Nature Link
Designing small molecules able to target multiple receptors might sound difficult, but Septerna says the allosteric binding site it has discovered is even better conserved across all incretin receptors than the site targeted by peptides and other small molecule drugs
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“I get to wake up and just worry about the normal daily tasks,” she says, “and not, ‘Am I going to be able to function today?’” Related: 6 Things a Wonky Period Might Be Telling You About Your Health What’s Up With the Luteal Phase and Is It the Reason I’m in Hell Right Now
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