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When prediction models are trained to forecast hard outcomes, such as a sustained ≥40% eGFR decline, ESKD, or major cardio-renal events, they are directly aligned with thresholds that clinicians already recognize as actionable end points (93)
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Estudios recientes han confirmado estos resultados en pacientes con diabetes tipo 2 y obesidad, mostrando diferencias de hasta 6% más de pérdida de peso frente a semaglutida
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