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GLP-1 injection site reaction: causes, symptoms, and how to treat every type - SeekPeptides
GLP-1Rs are widely distributed in several cells, such as islet cells (especially β-cells of the pancreas), endothelial cells, neurons, adipocytes, keratinocytes, lymphocytes, hepatocytes, smooth muscle cells, myocytes, Brunner’s glands in the duodenum, and myenteric plexus neurons in the gut 31,32,33,34
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For senescence of VSMCs, GLP-1RAs activate Nrf2 and inhibit Rac1 through cAMP/PKA pathways to prevent Ag II-induced senescence [122, 123]
