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90,91 In more severe cases of nausea and vomiting, prescribing antiemetics may be considered
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Specifically, a decline in renal perfusion pressure, decreased sodium chloride delivery to macula densa cells, and SNS-mediated stimulation of renal juxtaglomerular apparatus (primarily via β1-adrenergic receptors) trigger enhanced secretion of renin, a proteolytic enzyme produced by specialized juxtaglomerular cells in the kidney [68]
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